The Science

We don't ask you to trust us. We show you the research.

22 peer-reviewed studies. 4 ingredients. Every dose transparently labeled.

THE CORTISOL PROBLEM

The hormone behind everything you're feeling.

Cortisol regulates your sleep, your weight, your mood, your focus, and your immune system. When it stays elevated — and for 77% of adults it does — everything downstream breaks. Here's what that looks like over a single day.

Your cortisol (stressed)
Healthy cortisol
With Sakureva (after 60 days)*
High Normal Low ↓ lower
6 AM 9 AM 12 PM 3 PM 6 PM 9 PM 12 AM

6 AM

Wake up tired
Cortisol spikes before you even open your eyes. Already in overdrive.

12 PM

Running on caffeine
Should be declining. Instead it's still elevated. Third coffee it is.

6 PM

😤

Wired but exhausted
Body is done. Brain won't stop. Still running on stress hormones.

12 AM

😳

Can't fall asleep
Cortisol should be at its lowest. Yours is still elevated. Hello, ceiling.

One drink a day. Your cortisol back where it belongs.

THE CORTISOL PROBLEM

This isn't a wellness trend. It's a public health problem.

77%

of adults experience physical symptoms caused by stress

American Psychological Association

73%

experience psychological symptoms of stress daily

American Psychological Association

42%

of adults are Vitamin D deficient — making cortisol harder to regulate

National Health & Nutrition Survey

This isn't about being "too stressed." It's about a biological system that was designed for short bursts of danger — now running 24/7 in response to emails, traffic, and deadlines.

CHRONIC CORTISOL ELEVATION IS LINKED TO:

Increased abdominal fat storage
Epel et al., 2000 — Psychoneuroendocrinology

Disrupted sleep architecture
Buckley & Schatzberg, 2005 — J Clinical Endocrinology

Impaired memory and cognitive function
Lupien et al., 2007 — Nature Reviews Neuroscience

Weakened immune response
Segerstrom & Miller, 2004 — Psychological Bulletin

Increased inflammation markers
Black, 2002 — Brain, Behavior & Immunity

This isn't about being "too stressed." It's about a biological system stuck in overdrive.

Wellora was built around one question: what if we could bring cortisol back to where it belongs?

WHAT'S INSIDE

Four ingredients. Every one backed by research.

We picked the ones with the strongest clinical evidence and show you exactly what's in every serving.

KSM-66® Ashwagandha

INGREDIENT 01

KSM-66® Ashwagandha

150mg

The most clinically studied adaptogen on earth.

WHAT IT DOES

KSM-66 is a patented extraction of Withania somnifera that uses only the root — not the leaves, not a mix. It modulates your HPA axis, the system that controls cortisol release. When that system is overactive, you get chronic stress. KSM-66 helps recalibrate it.

THE STUDIES — KSM-66® ASHWAGANDHA

STUDY 1

Cortisol Reduction

Chandrasekhar et al., 2012 — Indian J Psychological Medicine · 64 subjects, 60 days, double-blind RCT

→ 27.9% reduction in serum cortisol

STUDY 2

Stress & Anxiety

Salve et al., 2019 — Cureus · 58 subjects, 8 weeks, double-blind RCT

→ Significant reduction in PSS scale + cortisol vs placebo

STUDY 3

Sleep Quality

Langade et al., 2019 — PLOS One · 150 subjects, 6 weeks, double-blind

→ 72% improvement in sleep quality (insomnia group)

STUDY 4

Cognitive Function

Choudhary et al., 2017 — J Dietary Supplements · 50 subjects, 8 weeks, double-blind RCT

→ Significant improvement in reaction time and attention

STUDY 5

Hormonal Balance

Lopresti et al., 2019 — J Clinical Medicine · 60 male subjects, 8 weeks, double-blind

→ 15% cortisol reduction, 14.7% increase in DHEA-S

Magnesium Glycinate 200mg

Ingredient 02

Magnesium Glycinate 200mg

200mg

The mineral 75% of people are missing.

What it does

Magnesium is involved in over 300 biochemical reactions in your body. It regulates neurotransmitter function, melatonin production, and the parasympathetic nervous system. Glycinate is the most bioavailable form — ~80% absorption vs ~4% for cheap magnesium oxide.

The studies — Magnesium Glycinate

STUDY 1

Sleep Quality

Abbasi et al., 2012 — J Research in Medical Sciences · 46 subjects, 8 weeks, double-blind RCT

→ Improved sleep time, melatonin up, cortisol down

STUDY 2

Anxiety Reduction

Boyle et al., 2017 — Nutrients · Systematic review of 18 studies

→ Consistent anxiolytic effects, strongest in low-magnesium subjects

STUDY 3

HPA Axis Modulation

Pickering et al., 2020 — Nutrients · Systematic review

→ Low magnesium = increased cortisol; supplementation reduced stress

STUDY 4

Muscle Recovery

Garrison et al., 2012 — Cochrane Database · Systematic review

→ Reduced muscle cramp frequency, glycinate best tolerated

STUDY 5

Depression Improvement

Tarleton et al., 2017 — PLOS One · 126 adults, 6 weeks, crossover

→ Significant PHQ-9 + GAD-7 improvement within 2 weeks

L-Theanine 

Ingredient 03

L-Theanine 

300mg

Calm focus without drowsiness. No caffeine needed.

What it does

L-Theanine crosses the blood-brain barrier within 30 minutes and increases alpha brain wave activity — the frequency associated with relaxed alertness. It also modulates GABA, serotonin, and dopamine, promoting calm without sedation.

The studies — L-Theanine

STUDY 1

Alpha Brain Waves

Nobre et al., 2008 — Nutritional Neuroscience · Controlled crossover trial

→ Significant alpha wave increase within 40 minutes at 200mg

STUDY 2

Stress Response

Kimura et al., 2007 — Biological Psychology · 12 subjects, crossover

→ Reduced heart rate + salivary stress markers during stress task

STUDY 3

Anxiety Reduction

Hidese et al., 2019 — Nutrients · 30 subjects, 4 weeks, double-blind RCT

→ Reduced PSQI + STAI scores, improved verbal fluency

STUDY 4

Cognitive Performance

Owen et al., 2008 — Nutritional Neuroscience · 27 subjects, acute dose

→ Improved accuracy + simultaneous alertness and calm

STUDY 5

Sleep Efficiency

Lyon et al., 2011 — Alternative Medicine Review · 98 subjects, 6 weeks

→ Significantly improved sleep percentage scores, no adverse effects

QUALITY VS THE MARKET

Most brands use the cheapest form. We use the best.

Same ingredient name on the label. Completely different quality inside. Here's what we actually use — and why it matters.

INGREDIENT
WHAT MOST BRANDS USE
WHAT SAKUREVA USES
Ashwagandha
Generic root powderUNSTANDARDIZED

No guaranteed withanolide content

KSM-66® Root Extract

Patented, standardized, 22 clinical studies

Magnesium
Magnesium Oxide~4% ABSORBED

Most passes right through you

Magnesium Glycinate

~80% bioavailability, no laxative effect

L-Theanine
Synthetic isolateUNVERIFIED PURITY

Often underdosed at 50-100mg

Pharmaceutical-grade L-Theanine

200mg — the dose used in alpha wave studies

Vitamin D
Vitamin D2 (ergocalciferol)LESS EFFECTIVE

Less bioavailable, shorter-acting

Vitamin D3 (cholecalciferol)

The active form your body actually uses

FAQs

Questions? We got you.

the results of our community speak for themselves

The future of foot care

From hand-picked Sakura blossoms to our Cold-Press extraction technique, our team blends centuries-old Japanese rituals with modern restorative science to create a heel stick that actually works.

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